Cases & Partnerships
Across 15 therapeutic areas and in partnership with over 30 world‑leading healthcare companies, non-profit organizations and providers Evoleen has delivered diverse projects and built scalable solutions that shape the future of healthcare.
Our Cases: Real Challenges. Real Solutions. Real Impact.
A Selection of Our End-to-End Projects

SIVA: Continuous cough monitoring supported by artificial Intelligence.
SIVA is a health start-up transforming chronic cough management by delivering 24/7 objective, real-time cough profiles through advanced voice biomarker technology, powered by machine learning and validated through partnerships with leading healthcare companies and researchers.
Read more about SIVA
The Challenge
- 10 % of persons worldwide
are affected by chronic cough - Continuous and objective cough monitoring is critical
- No clinically viable solution was available on the market to meet this need
Our goal was to build the first easy-to-wear cough monitor that delivers continuous, real-world cough data.
Evoleen‘s end2end Approach
- Problem understanding Phase with Pharma Partner
- Solution ideation and first concept testing
- Iterative product development
- Venture building & Clinical Trials
Solution, Results & Impact
- First Class II-certified AI, wearable, and
app for continuous 24/7 cough monitoring with superior performance

DigeHealth: Enhanced monitoring and improved therapy efficacy in gastroenterology.
DigeHealth is a platform-based DTx for gastrointestinal patients, combining a smart medical tracker with patient-reported context and AI-driven data models for comprehensive monitoring and insights.
Read more about DigeHealth
The Challenge
- 20 % of persons worldwide
are affected by
gastrointestinal problems - The gut is a black box – no continuous therapy monitoring is possible
- Patients suffer – Many don’t know what to eat
Our goal was to build the first easy-to-wear 24/7 bowel monitoring system.
Evoleen‘s Approach
- Problem understanding Phase with Pharma Partner
- Solution ideation and first concept testing
- Venture building & Clinical Trials
Solution, Results & Impact
- AI, wearable, and app for bowl sound monitoring

ProJo: The Future of trial monitoring
ProJo is a patient-facing chatbot and monitoring tool that enables seamless, real-time data collection in clinical trials and practice—achieving 97% data completeness with zero manual effort.
Read more about ProJo
The Challenge
- High dropout rates and poor-quality data in clinical trials threaten study validity & delay timelines.
- This may lead to costly repeat trials.
Our goal was to develop a digital tool with a smart interface that enables seamless data collection across patients and healthcare professionals.
Evoleen‘s Approach
- Problem worth solving analysis & Ideation
- HIPAA & GDPR compliant prototype
- Pilot trial
Solution, Results & Impact
- Patient Chatbot Interface & Monitoring Dashboard – Use of established means of communication
- 97% data collection with 0% manual effort

Collabree: Adherence Solution
Sticky habits made easy: Collabree is an app-based DTx for hypertension that goes beyond reminders—motivating patients, rewarding healthy habits, and driving lasting behavior change to improve outcomes and reduce healthcare costs.
Read more about Collabree
The Challenge
- Low therapy adherence caused by present bias, lack of habit, limited health literacy, and inadequate support
- This leads to poor outcomes, more complications, and rising healthcare costs
Our goal was to create adherent behaviour through daily actions and rewards by offering a digital companion.
Evoleen‘s Approach
- Problem understanding Phase with Pharma
Partner - Rapid Prototyping
- Drafted regulatory strategy
- Venture building & Clinical studies
Solution, Results & Impact
- Digital companion app (Medical Device Class I)
- Significant improvement of adherence

K!M: Transforms patient onboarding—Smarter, faster, safer.
KIM revolutionizes patient onboarding with a co-pilot, saving time for hospitals while ensuring complete
patient education. It streamlines education, consent & hospital stay information, offers individualized
processes & integrates with existing HIS.
Read more about K!M
The Challenge
- 6 million patients have to undergo a paper & pen premedication assessments for anesthesia every year, which takes each time about 5-30 minutes.
Our goal was to create a platform that allows patients to complete their premedication assessments remotely.
Evoleen‘s Approach
- Solution ideation and first concept testing
- MVP development & pilot trial
- Pitch deck creation
Solution, Results & Impact
- Virtual, adaptable clinical & patient platform
- Time savings through the elimination of routine tasks
- Seamless integration and flexible adaptation to clinical systems and requirements

Carity: Prevents secondary Cardiac Events.
After an infarction, it is an emotional up and down! Patient suffer from a loss of confidence, which can lead to decreased activity and thus slower cardiac recovery. Combined with a lack of motivation and inconsistent adherence to the therapy program, this leads to a poor outcome or an increased risk of another cardiac event.
Read more about Carity
The Challenge
- Only 54% of patients adhere to prescribed exercise in cardiac rehab follow-up programs
- Up to 80% of patients discontinue exercise within the first year after completing cardiac rehab
Our goal was to enable patients to build a long lasting, personalized cardiac rehabilitation after acute myocardial infarction.
Evoleen‘s Approach
- Problem understanding Phase with Pharma Partner
- Solution ideation and first concept testing
- Venture building & Clinical trial
Solution, Results & Impact
- Digital companion app
- Multi Site clinical study ongoing

WINGS: Holistic care for cancer patients.
After an infarction, it is an emotional up and down! Patient suffer from a loss of confidence, which can lead to decreased activity and thus slower cardiac recovery. Combined with a lack of motivation and inconsistent adherence to the therapy program, this leads to a poor outcome or an increased risk of another cardiac event.
Read more about WINGS
The Challenge
Cancer patients lack personalized non-medical support, leading to over 700 million CHF in avoidable annual costs.
Our goal was to enable patients to access informational materials from the KL and support them throughout their treatment journey.
Evoleen‘s Approach
- Problem understanding Phase with Partner
- Solution ideation and first concept testing
- Rapid Prototyping
Solution, Results & Impact
- Non-medical-device solution for cancer treatment journey
- Usability (SUS 79)
- +1300 Users within approx. 12 months
Explore more projects
Hello Mirrors brings digital prevention to care facilities.
Developed by physiotherapists and medical experts, the Health Mirror enables users to perform guided exercises anytime, keeping motivation high through gamified feedback and real-time motion reflection.
Evoleen supported Hello Mirrors with coaching, investment, and access to our investor network, helping refine their market assessment and business model — paving the way for broader adoption and sustainable growth.
AssureYou empowers pregnant women with 24/7 reassurance through remote ultrasound.
By distributing Pulsenmore, a GE Healthcare innovation, AssureYou enables clinician- or app-guided self-scans that enhance access and continuity of prenatal care.
Evoleen supported the team in building the company, recruiting medical partners, conducting market assessment and telehealth pilots, and refining the go-to-market and sales model. We also introduced a new rental approach and supported outreach to practices and gynecologists — driving adoption of remote pregnancy monitoring in Switzerland.
Hospital@Home enables acute care where patients recover best — at home.
This Swiss startup is transforming how acute conditions are treated, shifting care from hospitals to patients’ homes.
To accelerate their growth, Evoleen supported them by developing a compelling pitch deck, refining their business case, setting up a cap table, and facilitating access to our investor network — paving the way for successful fundraising and expansion.
Understanding tissue mechanics can transform healthcare and everyday life.
Founded in 2016, CITUS developed NIMBLE — a non-invasive device that characterizes soft tissue mechanics for early skin fibrosis detection and scar monitoring after burns. By bridging mechanics and medicine, CITUS enables more precise diagnostics and personalized treatments across healthcare and cosmetics.
“With Evoleen, we have a strong partner in regulatory expertise supporting our journey to make NIMBLE the new clinical gold standard for skin assessment.”
The Swiss company machineMD revolutionizes neurological diagnostics through eye-tracking in VR.
By combining advanced eye-tracking technology with proprietary examination protocols, neos® enables objective assessment of brain function. Its cloud-based platform supports telemedicine applications, allowing specialists worldwide to access and analyze patient data seamlessly.
machineMD entered into a strategic partnership with Evoleen to revolutionize early detection of brain disorders. While machineMD develops the device, Evoleen advances the software development and web application and manages the cloud infrastructure. With the cloud solution, data generated by neos™can be made accessible to doctors around the world. This enables better diagnostic capabilities, geographical barriers can be overcome, and collaboration as well as an exchange of knowledge and experience can take place between professionals on a global scale.